Worldwide, there are an estimated 140 million preschool children and 7.2 million pregnant women who have vitamin A deficiency (597). In low-income countries worldwide, there are an estimated 453,000 children with blindness or severe visual impairment, and 200,000 have corneal scarring attributed mostly to measles and vitamin A deficiency (2). There is a close synergism between measles and vitamin A deficiency that can result in blindness, and of an estimated 30 million children who develop measles each year, there are an estimated 15,000-60,000 children who become blind (598). Others have suggested that there may be about 350,000 children who go blind from vitamin A deficiency annually (599).
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