Prostate Cancer

Prostate-specific membrane antigen (PSMA) is a glycoprotein normally located within the intracellular compartment in normal prostate epithelium. However, upon neoplastic transformation, this protein exists as a type II membrane protein. The work using VRPs as a vector system targeting PSMA has been reported in abstract form only (131,132). The full-length PSMA-coding sequence was used for heterologous protein expression in the

VRP system. Mice were immunized with VRPs designed to express this xenoantigen and both antibody and cellular immune responses were identified. Both responses were reflective of a Th1 bias to the elicited immune responses as characterized by cytokine production, IFN-y and IL-4, for CD4 and CD8 T cells by ELISPOT and murine antibody isotype.

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10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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