B TAFContaining Complexes

Similar to TBP that forms SL1, TFIID, TFIIIB, and TAC complexes, some TAF components in TFIID are also present in distinct complexes such as TBP-free TAFn-containing complex TFTC , Spt-Ada-Gcn5-acetyltransferase SAGA , Spt3-TAFn31-GCN5L i.e., the long form of GCN5 acetylase STAGA , and polycomb repressive complex 1 PRC1 . These TBP-lacking TAF-containing complexes are involved in diverse aspects of pol II-dependent transcription. Except PRC1 whose role is mainly in gene silencing, the other...