T

T2. see 3,3'-Diiodothyronine (T2) T3. see 3,3',5-Triiodothyronine (T3) T4. see Thyroxine (T4) Tamoxifen effects of, 293, 295 estrone inhibition, 167 induction of SULT1A1, 211 and SULT1A1*2 allele, 66 TATA box, 209-210 TCDD, 212 Terbutaline stereoselective sulfation, 162-163 sulfonation of, 215 Testosterone

DHEA inhibition, 167 sulfation rates, 157, 161-162 sulfoconjugation and aging, 243 SULT2A sulfation, 234, 270 3,3,5,5'-Tetrachloro-4, 4'-biphenyldiol, 14 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 212 1,2,3,4-Tetrahydroisoquinolone, 157, 161-162

Thermolabile phenol sulfotransferase, 66, 90; see also SULT1A3 Thermostability and substrate specificity, 184 SULT1A1, 64-66, 88 Thermostable sulfotransferase, 64; see also

SULT1A1 Thiosulfate, formation of, 253 Third International Sulfation Workshop, 2 Thrombin, 244

Thromboxane B2, Sult1d1 sulfation, 13 Thyroid hormones conjugation reactions, 122 effects of sulfation, 110 and fetal development, 109-110 glucuronidation of, 122 metabolism, 109-110, 214 regulation, 121-122 sulfation, 1, 123-124, 129-130, 259 SULT1, 203-204 SULT1B, 13, 92 Thyroid hormone-sulfating sulfotransferase, 92; see also SULT1B1

L-Thyrosine, 259

Thyroxine (T4) sulfation, 109, 121, 128 SULT1, 124-126 SULT1E1, 113 SULT4A1, 15 SULT7A1, 15 Thyroxine (T4) sulfate, 123 Tibolone, 144-145, 147, 149 Tolfenamic acid, 168 Trachea, SULT2B1 expression, 86 Transforming growth factor (TGF)-|31, 142 Transglutaminase I, 245 reverse3,3',5-Triiodothyronine (rT3), 109-110, 121, 128 in fetal serum, 129 sulfation, 113, 124-126 reverse3,3',5-Triiodothyronine (rT3) sulfate, 123 3,3',5-Triiodothyronine (T3), 121, 128 bioavailability, 109 in fetal serum, 129 sulfation,

SULT1, 124-126 SULT1D, 13 SULT1E1, 113 SULT4A1, 15 SULT7A1, 15 Troglitazone, sulfation rates, 262 Tumor-suppressor genes, 279 Turnover numbers, SULTs, 28 Tyr81, 36

Tyr81/Phe142 gate, 36-37 Tyramine, 262 Tyrosine, 36, 88, 215 Tyrosylproteins, 2

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