The DREZ operation has provided substantial relief of pain for thousands of patients who otherwise would have continued to suffer from their condition. Many pain syndromes previously deemed "untreatable'' have become more manageable. Even anesthesia dolorosa, the dreaded complication of a minority of trigeminal neuralgia procedures, can yield to the nucleus caudalis DREZ operation in a significant number of cases. The DREZ is generally not useful for peripheral etiology pain in the spinal cord (eg, chronic back pain, postherpetic neuralgia, neuropathic pain, and causalgia), although it has a more reliable effect for such peripheral pains in the trigeminal distribution (ie, pain after dental procedures, infections, or trauma) through the nucleus caudalis.
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