Pathological potential of activated microglia

As is the case for macrophages in many body systems, microglia are capable of providing both protection and destruction. The exaggerated or prolonged activation of microglial cells can be detrimental to the brain. In certain cases, the pathological activation of microglia may have a decisive input into the pathological developments. This may happen, for example, in infectious diseases, in particular in certain types of bacterial infection or in prion diseases (see Chapter 10). Similarly, chronic neurodegenerative diseases (e.g. Alzheimer's or Parkinson's disease - Chapter 10) may underlie the long-lasting over-activation of microglial cells, which subsequently may produce neuronal or astroglial death.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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