Irradiation therapy of gliomas often results in cognitive and memory decline of a yet undiscovered nature. One of the current hypotheses highlights the role of activated hippocampal microglia, which may interfere with neurogenesis. Indeed it was found that irradiation of the brain causes activation of microglia and inhibition of neurogenesis; a very similar result was obtained after intra-hippocampal injections of LPS, which is a powerful microglial activator. Neurogenesis can be restored and activation of microglia placated by anti-inflammatory drugs such as indomethacin, or by inhibitors of microglial activation such as minocycline.
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Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.