References

Amitai G, Belenkiy O, Dassa B, Shainskaya A, Pietrokovski S (2003) Distribution and function of new bacterial intein-like protein domains. Mol Microbiol 47:61-73 Amitai G, Dassa B, Pietrokovski S (2004) Protein splicing of inteins with atypical glutamine and aspartate C-terminal residues. J Biol Chem 279:3121-3131 Chen L, Benner J, Perler FB (2000) Protein splicing in the absence of an intein penultimate histidine, J Biol Chem 275:20431-20435 Chong S,Xu M-Q (1997) Protein splicing of the Saccharomyces cerevisiae VMA intein without the endonuclease motifs. J Biol Chem 272:15587-15590 Chong S, Shao Y, Paulus H, Benner J, Perler FB, Xu M-Q (1996) Protein splicing involving the Saccharomyces cerevisiae VMA intein: the steps in the splicing pathway, side reactions leading to protein cleavage, and establishment of an in vitro splicing system. J Biol Chem 271:22159-22168 Chong S, Mersha FB, Comb DG, Scott ME, Landry D, Vence LM, Perler FB, Benner J, Kucera R, Hirvonen CA, Pelletier JJ, Paulus H,Xu M-Q (1997) Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element. Gene 192:271-281 Chong S, Montello GE, Zhang A, Cantor EJ,Liao W,Xu M-Q, Benner J (1998a) Utilizing the C-terminal cleavage activity of a protein splicing element to purify recombinant proteins in a single chromatographic step. Nucleic Acids Res 26:5109-5115 Chong S, Williams KS, Wotkovicz C, Xu M-Q (1998b) Modulation of protein splicing of the Saccharomyces cerevisiae vacuolar membrane ATPase intein. J Biol Chem 273:1056710577

Clarke S (1987) Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins. Int J Peptide Protein Res 30:808-821 Cooper AA, Chen Y-J, Lindorfer MA, Stevens TH (1993) Protein splicing of the yeast TFP1

intervening protein sequence: a model for self-excision. EMBO J 12:2575-2583 Dalgaard JZ, Moser MJ, Hughey R, Mian IS (1997) Statistical modeling, phylogenetic analysis and structure prediction of a protein splicing domain common to inteins and hedgehog proteins. J Comput Biol 4:193-214 Dassa B, Haviv H, Amitai G, Pietrokovski S (2004) Protein splicing and auto-cleavage of bacterial intein-like domains lacking a C'-flanking nucleophilic residue. J Biol Chem 279:32001-32007

Derbyshire V, Wood DW, Wu W, Dansereau JT, Dalgaard LZ, Beifort M (1997) Genetic definition of a protein-splicing domain: functional mini-inteins support structure predictions and a model for intein evolution. Proc Natl Acad Sei USA 94:11466-11471 Ding Y,Xu M-Q, Ghosh I, Chen X, Ferrandon S, Lesage G, Rao Z (2003) Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J Biol Chem 278:39133-39142 Duan X, Gimble FS, Quiocho FA (1997) Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell 89:555-564 Evans TC,Xu M-Q (2002) Mechanistic and kinetic considerations of protein splicing. Chem Rev 102:4869-4883

Evans TC, Martin D, Kolly R, Panne D, Sun L, Ghosh I, Chen L, Benner J, Liu X-Q, Xu M-Q (2000) Protein frans-splicing and cyclization by a naturally split intein from the dnaE gene of Synechocystis species PCC6803. J Biol Chem 275:9091-9094 Geiger T, Clarke S (1987) Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation. J Biol Chem 262:785-794 Hall TM. T, Porter JA, Young KE, Koonin EV, Beachy PE, Leahy DJ (1997) Crystal structure of a hedgehog protein autoprocessing domain: homology between hedgehog and self-splicing proteins. Cell 91:85-97 Hirata R, Anraku Y (1992) Mutations at the putative junction sites of the yeast VMA1 protein, the catalytic subunit of the vacuolar H+-ATPase, inhibit its processing by protein splicing. Biochem Biophys Res Commun 188:40-47 Hirata R, Ohsumi Y, Nakano A, Kawasaki H, Suzuki K, Anraku Y(1990) Molecular structure of a gene, VMA1, encoding the catalytic subunit of H+-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J Biol Chem 265:6726-6733

Iwai K, Ando T (1967) N-0 acyl rearrangement. Methods Enzymol 11:262-282 Jencks WP, Cordes S, Carriulo J (1960) The free energy of thiol ester hydrolysis. J Biol Chem 235:3608-3614

Kane PM, Yamashiro CT, Wolczyk DF, Neff N, Goebl M, Stevens TH (1990) Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar ^-adenosine triphosphatase. Science 250:651-657 Kawasaki M, Nogami S, Satow Y, Ohya Y, Anraku Y (1997) Identification of three core regions essential for protein splicing of the yeast Vmal protozyme. A random mutagenesis study of the entire Vmal-derived endonuclease sequence. J Biol Chem 272:15668-15674 Klabunde T, Sharma S, Telenti A, Jacobs WR, Sacchettini JC (1998) Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing. Nat Struct Biol 5:31-36

Lew BM, Mills KV, Paulus H (1999) Characteristics of protein splicing in trans mediated by a semisynthetic intein. Biopolymers (Peptide Sci) 51:355-362 Martin DD,Xu M-Q, Evans TC (2001) Characterization of a naturally occurring trans-splicing intein from Synechocystis sp. PCC6803. Biochemistry 40:1393-1402 Mathys S, Evans TC, Chute IC, Wu H, Chong S, Benner J, Liu X-Q,Xu M-Q (1999) Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: facile production of protein building blocks for protein ligation. Gene 231:1-13 Mills KV, Paulus H(2001) Reversible inhibition of protein splicing by zinc ion. J Biol Chem 241:10832-10838

Mills KV, Lew BM, Jiang S-Q, Paulus H (1998) Protein splicing in trans by purified N- and C-terminal fragments of the Mycobacterium tuberculosis RecA intein. Proc Natl Acad Sci USA 95:3453-3458

Mills KV, Manning JS, Garcia AM, Wuerdeman LA (2004) Protein splicing of a Pyrococcus abyssi intein with a C-terminal glutamine. J Biol Chem 279:20685-20691 Mizutani R, Nogami S, Kawasaki M, Ohya Y, Anraku Y, Satow Y (2002) Protein splicing reaction via a thiazolidine intermediate; crystal structure of the VMAl-derived endonuclease bearing the N- and C-terminal propeptides. J Mol Biol 316:919-929 Mizutani R, Anraku Y, Satow Y (2004) Protein splicing of yeast VMAl-derived endonuclease via thiazolidine intermediates. J Synchrotron Rad 11:109-112 Muir TW (2003) Semisynthesis of proteins by expressed protein ligation. Annu Rev Biochem 72:249-289

Nichols NM, Evans TC (2004) Mutational analysis of protein splicing, cleavage, and self-association reactions mediated by the naturally split Ssp DnaE intein. Biochemistry 43:10265-10276

Nichols NM, Benner JS, Martin DD, Evans TC Jr (2003) Zinc ion effects on individual Ssp DnaE intein splicing steps: regulating pathway progression. Biochemistry 42:53015311

Nogami S, Satow Y, Ohya Y, Anraku Y (1997) Probing novel elements for protein splicing in the yeast Vmal protozyme: a study of replacement mutagenesis and intragenic suppression. Genetics 147:73-85 Noren CJ, Wang J, Perler FB (2000) Dissecting the chemistry of protein splicing and its applications. Angew Chem Int Ed 39:451-466 Paulus H (1998) The chemical basis of protein splicing. Chem Soc Rev 27:375-386 Paulus H (2000) Protein splicing and related forms of protein autoprocessing. Annu Rev

Biochem 69:447-496 Paulus H (2001) Inteins as enzymes. Bioorg Chem 29:119-129 Perler FB (2002) InBase, the intein database. Nucleic Acids Res 30:383-384 Perler FB,Xu M-Q, Paulus H (1997) Protein splicing and autoproteolysis mechanisms. Curr

Opin Chem Biol 1:292-299 Pietrokovski S (1994) Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins. Protein Sei 3:2340-2350 Pietrokovski S(1998) Modular organization of inteins and C-terminal autocatalytic domains. Protein Sei 7:64-71 Poland BW, Xu M-Q, Quiocho FA (2000) Structural insights into the protein splicing mechanism of PI-SceI. J Biol Chem 275:16408-16413 Porter JA, Ekker SC, Park WJ, Kessler DP, Young KE, Chen CH, Ma Y, Woods AS, Cotter RJ, Koonin EV, Beachy PA (1996a) Hedgehog patterning activity: role of lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell 86:21-34 Porter JA, Young KE, Beachy PA (1996b) Cholesterol modification of hedgehog signaling proteins in animal development. Science 274:255-259 Ramachandran GM, Mitra AK (1976) An explanation for the rare occurrence of eis peptide units in proteins and polypeptides. J Mol Biol 107:85-92 Romanelli A, Shekhtman A, Cowburn D, Muir TW (2004) Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction. Proc Natl Acad Sei USA 101:6397-6402 Shao Y, Paulus H (1997) Protein splicing: estimation of the rate of O-N and S-N acyl rearrangements, the last step of the splicing process. J Peptide Res 50:193-198 Shao Y,Xu M-Q, Paulus H (1995) Protein splicing: characterization of the aminosuccimide residue at the carboxyl terminus of the excised intervening sequence. Biochemistry 34:10844-10850

Shao Y,Xu M-Q, Paulus H (1996) Protein splicing: evidence for an N-0 acyl rearrangement as the initial step in the splicing process. Biochemistry 35:3810-3815 Shingledecker K, Jiang S-Q, Paulus H (1998) Molecular dissection of the Mycobacterium tuberculosis RecA intein: design of a minimal intein and of a trans-splicing system involving two intein fragments. Gene 207:187-195 Shingledecker K, Jiang S-Q, Paulus H (2000) Reactivity of the cysteine residues in the protein splicing active center of the Mycobacterium tuberculosis RecA intein. Arch Biochem Biophys 375:138-144

Southworth MW, Adam E, Panne D, Byer R, Kautz R, Perler FB (1998) Control of protein splicing by intein fragment reassembly. EMBO J 17:918-926

Southworth MW, Amaya K, Evans TC, Xu M-Q, Perler FB (1999) Purification of proteins fused to either the amino or carboxy terminus of the Mycobacterium xenopii gyrase A intein. Biotechniques 27:110-120 Southworth MW, Benner J, Perler FB (2000) An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile. EMBO J 19:1-8 Southworth MW, Perler FB (2002) Protein splicing of the Deinococcus radiodurans strain

R1 Snf2 intein. J Bacteriol 184:6387-6388 Southworth MW, Yin J, Perler FB (2004) Rescue of protein splicing activity from a Magne-

tospirillum magnetotacticum intein-like element. Biochem Soc Trans 32:250-254 Telenti A, Southworth M, Alcaide F, Daugelat S, Jacobs WR, Perler FB (1997) The Mycobacterium xenopi GyrA protein splicing element: characterization of a minimal intein. J Bacteriol 179:6378-6382 Voorter CEM, de Haard-Hoekman WA, van den Oetelaar PJM, Bloemendal H, de Jong WW (1988) Spontaneous peptide bond cleavage in aging a-crystallin through a succinimide intermediate. J Biol Chem 263:19020-19023 Wang S, Liu X-Q (1997) Identification of an unusual intein in chloroplast ClpP protease of

Chlamydomonas eugametos. J Biol Chem 272:11869-11873 Wood DW, Wu W, Beifort G, Derbyshire V, Beifort M (1999) A genetic system yields self-

cleaving inteins for bioseparations. Nat Biotechnol 17:889-892 Wu H, Hu Z, Liu X-Q (1998) Protein frans-splicing by a split intein encoded in a split DnaE

gene of Synechocystis sp. PCC6803. Proc Natl Acad Sei USA 95:9226-9231 Xu M-Q, Perler FB (1996) The mechanism of protein splicing and its modulation by mutation. EMBO J 15:5146-5153 Xu M-Q, Southworth MW, Mersha FB, Hornstra LJ, Perler FB (1993) In vitro protein splicing of purified precursor and the identification of a branched intermediate. Cell 75:1371-1377

Xu M-Q, Comb DG, Paulus H, Noren CJ, Shao Y, Perler FB (1994) Protein splicing: an analysis of the branched intermediate and its resolution by succinimide formation. EMBO J 13:5517-5522

Yamamoto K, Low B, Rutherford SA, Rajagopalan M, Madiraju MV (2001) The Mycobacterium avium-intracellulare complex dnaB locus and protein intein splicing. Biochem Biophys Res Commun 280:896-903 Yamazaki T, Otomo T, Oda N, Kyogoku Y, Uegaki K, Ito N, Ishino Y, Nakamura H (1998) Segmental isotope labeling for protein NMR using peptide splicing. J Am Chem Soc 120:5591-5592

Was this article helpful?

0 0

Post a comment