Weight Loss

The most recent of the studies examining weight control were designed to address concerns about long-term safety and efficacy for weight loss using a mixture containing 90 mg of ephedrine (from ephedra) and 192 mg of caffeine, derived from cola nuts (15). A 6-month randomized, double-blind, placebo-controlled trial was performed, in which a total of 167 subjects (body mass index 31.8 ± 4.1 kg/m2) were randomized to receive either placebo (n = 84) or herbal treatment (n = 83). The primary outcome measurements were changes in blood pressure, heart function, and body weight. Secondary variables included body composition and metabolic changes. It was found that herbal vs placebo treatment decreased body weight (-5.3 ± 5.0 vs -2.6 ± 3.2 kg, P < 0.001), body fat (-4.3 ± 3.3 vs -2.7 ± 2.8 kg, P = 0.020), and low-density lipoprotein cholesterol (-8 ± 20 vs 0 ± 17 mg/dL, P = 0.013), and increased high-density lipoprotein cholesterol (+2.7 ± 5.7 vs -0.3 ± 6.7 mg/ dL, P = 0.004). Herbal treatment produced small changes in blood pressure variables (+3 to -5 mmHg, P<0.05), and increased HR (4 ± 9 vs -3 ± 9 beats per minute, P < 0.001), but cardiac arrhythmias were not increased (P > 0.05). By self-report, dry mouth (P < 0.01), heartburn (P < 0.05), and insomnia (P < 0.01) were increased and diarrhea decreased (P < 0.05). Irritability, nausea, chest pain, and palpitations did not differ, nor did numbers of subjects who withdrew. CONCLUSIONS: In this 6-month placebo-controlled trial, herbal ephedra/caffeine (90/192 mg/day) promoted body-weight and body-fat reduction and improved blood lipids without significant adverse events.

Dieting Dilemma and Skinny Solutions

Dieting Dilemma and Skinny Solutions

The captivating thing about diets is that you don't get what is researched or predicted or calculated but rather, you get precisely what you expect. If the diet resonates with you then it will likely work, if it doesn't resonate, it won't.

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