The habitats in which xenosaurids are found range from cool, tropical cloud forests to fairly dry and hot scrub habitats. All species apparently share a crevice- or hole-dwelling habit. In fact, very few Xenosaurus have ever been found outside of a crevice or hole.

Habitat appears to influence the ability of xenosaurids to thermoregulate. Species and populations from rain or cloud forests are unable to raise their body temperatures independently of the environment, whereas those from more open, scrub habitats are able to elevate their body temperatures above the environment's temperature.

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