Most recent phylogenetic analyses have placed amphisbaenians as one of three suborders of Squamates (the clade that includes snakes, lizards, and amphisbaenians), but their exact placement within that clade is not well understood. The interrelationships among the four amphisbaenian families are also poorly understood. The Amphisbaenidae has no significant fossil record; a few isolated remains occur in Europe and in Africa. Amphisbaenids are possibly most closely related to trogonophids based on a recent phylogenetic analysis of the group. This is the largest and most heterogeneous amphis-baenian family. No subfamilies are recognized.
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