Info

fio

Yin

Designation R C-24

Designation R C-24

Pseudoginsenoside Fn

-Glc2-Rha

CR)

rt2

-Glc2-Xyl

(R)

rt4

-Glc

(S)

rt5

-Glc

(R)

Quantitative analysis of the roots by Besso et al. (1981) and Zhou et al. (1981) provided the data listed in Table 5.29.

More recent work has indicated the presence of 14 known dammarane-type triterpene oligoglycosides, 9 new dammarane-type triterpene oligoglycosides named notoginsenosides A, B, C, D, E, G, H, I and J and an acetylenic fatty acid glycoside identified as notoginsenic acid ^-sophoroside (Yoshikawa et al., 1997). These compounds are interesting because the roots are valued in local medicine as haemostatic agents for both internal and external bleeding and as hepatoprotective agents.

Amongst other chemicals isolated from the roots of P. notoginseng are the peptides a-amino-^-(oxaloamino)propionic acid (Okan, 1982) and dencichin (3-[(carboxy-carbonyl)-amino]-L-alanine)(Zhao and Wang, 1986). Both compounds increase blood platelet numbers and enhance blood coagulation. P. notoginseng roots also yielded the polysaccharide sanchinan A (molecular weight 1.5x106), a compound with a ^-D-(1^3)-linked galactopyranosyl backbone with branching points at C-6 to which mainly a-L-arabinofuranosyl and partly ^-D-galacto-pyranosyl (1^6)-^-D-galactopyranosyl side chains are attached on average to 2 or 3 galactosyl units. Sanchinan A also incorporates a small

Table 5.29. Recorded yields of saponins of Panax pseudoginseng Wallich (P. notoginseng) roots

Designation

Prosapogenin

Recorded yield per cent

Total ginsenosides

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