Trisomy

Trisomy of chromosome 14 occurs only on mosaic basis in live births and is characterized by developmental and growth delay and characteristic facial features including prominent forehead, wide nasal bridge, low-set ears, cleft palate, and micrognathia; cardiac malformations are common. Ophthalmic features include hypo- and hypertelorism, downward slanting of the palpebral fissures, blepharoptosis, deep-set eyes, eversion of the eyelids, a "evanescent translucent film over the eyes," and microphthalmia 120,168,206,213,360,367

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