Duplication 3q

Partial trisomy of the long arm of chromosome 3, which is rare, is characterized by acro- and brachycephaly, hirsutism, facial features similar to the de Lange syndrome, synophrys, long eyelashes, hypogenitalism in both males and females, and cardiac malformations. Ophthalmic manifestations are common and include hypertelorism, epicanthus, up- or downward slanting of the palpebral fissures, synophrys, strabismus, nasolacrimal duct obstruction, cataract, corneal opacities, congenital glaucoma, nystagmus, and colobomatous microphthalmia.4-53-90-^S-1S3-301-316-337-36S-3S6-4^

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