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Fig. 3. Ethanol inhibition of NMDA receptors is not competitive with glycine. The graph plots the percentage of current activated by 50 |lM NMDA as a function of glycine concentration in the absence (filled circles) and presence (open circles) of 50 mMethanol. Each data point is the mean ± S.E. of at least seven neurons. The curves shown are the best fits of the data to the equation described in the legend to Fig. 1. Ethanol decreased the maximal response of the glycine concentration-response curve without changing the EC50 of glycine. (Data from ref. 40.)

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Natural Detox

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