Info

MK-801 (noncomp)

Rat

Stereotyped biting

Yes (but only high doses examined)

Livezey et al., 1995 (96)

MK-801 (noncomp)

Mouse

Locomotor stimulation

Yes (but only at high doses)

Iijima et al., 1996 (97)

MK-801 (noncomp)

Rat

Locomotor stimulation

Yes (but only at high doses)

Vanderschuren et al., 1996 (98)

MK-801 (noncomp)

Rat

Locomotor stimulation

Yes

Swadley-Lewellen and Trujillo, 1998 (76)

a Noncomp = noncompetitive antagonist; comp = competitive antagonist. The study of Tzschentke and Schmidt (75) is not included in this table. As discussed previously (70) and noted in Table 2, this study appears to have been misinterpreted, as sensitization was not observed in the course of the experiments.

a Noncomp = noncompetitive antagonist; comp = competitive antagonist. The study of Tzschentke and Schmidt (75) is not included in this table. As discussed previously (70) and noted in Table 2, this study appears to have been misinterpreted, as sensitization was not observed in the course of the experiments.

explored across different opiate effects in the same experimental animals, as this will allow for direct comparisons to be made across behaviors (25,29,76,77) (see ref. 70 for further discussion).

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