The major form of head and neck cancer is squamous cell carcinoma of the oral cavity. Therefore, attempts to study the experimental pathology of head and neck cancer were focused on the development of experimental models for oral cancer. Because the primary risk factors for oral cancer development are tobacco and alcohol, chemical carcinogens were used to induce oral cancers in animal models. Other investigations attempted to develop experimental models for malignant tumors of salivary glands, larynx, and other head and neck sites.
Head and Neck Cancer
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