The cells of the zona fasciculata are large and polyhedral. They are arranged in long straight cords, one or two cells thick, that are separated by sinusoidal capillaries. The cells of the zona fasciculata have a lightly staining spherical nucleus. Binucleate cells are common in this zone. TEM studies reveal characteristics typical of steroid-secreting cells, i.e., a highly developed sER (more so than cells of the zona glomerulosa) and mitochondria with tubular cristae. They
— zona glomerulosa
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