Cleavage of the procollagen molecule. Illustration showing the procollagen molecule with N- and C-terminals. Small curved arrows in the upper part of the illustration show where terminals are split from the procollagen molecule to form the collagen (tropocol-lagen) molecule. On the C-terminal of the molecule, the sugar subunit is GlcNac (N-acetylglucosamine) attached to mannose (Man)n. (Adapted from Prockop DJ, et al. N Engl J Med 1979;301:13-23. Copyright © 1979 Massachusetts Medical Society. All rights reserved.)
1 globular domain triple-helical domain nontriple-helical domain nontriple-helical domain
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