Figure 424

Molecular structure of hemidesmosome. a. Electron micrograph of the basal aspect of a gingival epithelial cell. Below the nucleus (N), intermediate filaments are seen converging on the intracellular attachment plaques (arrows) of the hemidesmosome. Below the plasma membrane are the basal lamina (BL) and collagen (reticular) fibrils (most of which are cut in cross section) of the connective tissue, x40,000. b. Diagram showing the molecular organization of a hemidesmosome. The intracellular attachment plaque is associated integrin fibronectin basement membrane

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