Schematic diagram of the basal portions of two epithelial cells. This diagram shows the cellular and extracellular components that provide attachment between epithelial cells and the underlying connective tissue. On the connective tissue side of the basal lamina, anchoring fibrils extend from the basal lamina to the collagen (reticular) fibrils of the connective tissue, providing structural attachment at this site. On the epithelial side, laminin (green), collagen XVII (red), and in-tegrins (yellow) are present in the lamina rara and lamina densa and provide adhesion between the basal lamina and the intracellular attachment plaques of hemidesmosomes.
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