Ovarian teratoma. In the center is a H&E-stained section of an ovarian teratoma seen at low magnification. This mass is composed of various basic tissues that are well differentiated and easy to identify at higher magnification. The abnormal feature is the lack of organization of the tissues to form functional organs. The tissues within the boxed areas are seen at higher magnification in micrographs a-f. xlO. The higher magnification allows identification of some of the basic tissues that are present within this tumor.

composed of less differentiated tissues that usually lead to malignancy. An example of a solid-mass ovarian teratoma containing fully differentiated tissue is shown in the center micrograph of Figure 3.5. The low power reveals the lack of organized structures but does not allow identification of the specific tissues present. However, with higher magnification, as shown in the insets (a-f), mature differentiated tissues are evident.

The example given in Figure 3.5 shows that one can readily identify tissue characteristics, even in an unorganized structure. Again, the important point is the ability to recognize aggregates of cells and to determine the special characteristics that they exhibit.

a. Simple columnar epithelium lining a cavity of a small cyst, x 170. Inset. Higher magnification of the epithelium and the underlying connective tissue. x320. b. Dense regular connective tissue forming a tendon-like structure. x170. c. Area showing hyaline cartilage (C) and developing bone spicules (B). x170. d. Brain tissue with glial cells. x170. e. Cardiac muscle fibers. X220. Inset. Higher magnification showing intercalated disks (arrows). X320. f. Skeletal muscle fibers cut in cross section. x220.

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layer, the dorsal ectoderm of the embryo. Some nervous system cells, such as ependymal cells and cells of the choroid plexus in the CNS, retain the absorptive and secretary functions characteristic of epithelial cells.

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