Figure 259

Structure of the nuclear lamina, a. This schematic drawing shows the structure of the nuclear lamina adjacent to the inner nuclear membrane. The cut window in the nuclear lamina shows the DNA within the nucleus. Note that the nuclear envelope is pierced by nuclear pore complexes, which allow for selective bidirectional transport of molecules between nucleus and cytoplasm, b. Electron micrograph of a portion of the nuclear lamina from a Xenopus oocyte. It is formed by intermediate filaments (lamins) that are arranged in a square lattice. x43,000. (Adapted from Aebi U, et al. Nature 1986;323: 560-564.)

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