Figure 226

Anterograde and retrograde transport between the rER and c/s-Golgi network. Two classes of coated vesicles are involved in protein transport to and from the rER. These vesicles are surrounded by COP-I and COP-II protein coat complex, respectively. COP-II is involved in anterograde transport from the rER to the c/s-Golgi network (CGN), and COP-I is involved in retrograde transport from the CGN back to the rER. After a vesicle is formed, the coat components dissociate from the vesicle and are recycled to their site of origin.


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