Figure 2223

Transformation zone of the cervix. The site of the squamocolumnar junction from the upper rectangle in Figure 22.21 is shown here at higher magnification. Note the abrupt change from stratified squamous epithelium to simple columnar epithelium (arrow). Neoplastic changes leading to development of cervical cancer most frequently begin in this transformation zone. Within the connective tissue are the branched, mucus-secreting cervical glands (CG) composed of a simple columnar epithelium that is continuous with the lining epithelium of the cervical canal. xl20.

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