Diagram of a brush cell and small granule cell. a. The brush cell, as illustrated here, is interposed between type I and type II alveolar cells of an alveolus. Blunt microvilli are distinctive features of the brush cell. The cytoplasm typically shows a Golgi apparatus, lysosomes, mitochondria, and glycogen inclusions, b. This small granule cell is shown located between two Clara cells, as in a terminal or respiratory bronchiole. The cell contains small secretory vesicles, most of which are in the basal portion of the cell. In addition to the vesicles, the most conspicuous organelles of the cell are rough-surfaced endoplasmic reticulum (rER), a Golgi apparatus, and mitochondria. A nerve terminal is shown within the epithelium adjacent to the cell.
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