Figure 1622

Diagram of a goblet cell. The nucleus is located at the basal portion of the cell. The major portion of the cell is filled with mucinogen granules forming the mucous cup that is evident in the light microscope. At the base and lower sides of the mucous cup are flattened saccules of the large Golgi apparatus. Other organelles are distributed throughout the remaining cytoplasm, especially in the perinuclear cytoplasm in the base of the cell. (Based on Neutra MR, Leblond CP. J Cell Biol 1966;30:119-136.)

Paneth cells play a role in regulation of normal bacterial flora of the small intestine

Paneth cells are found in the bases of the intestinal glands. (They are also occasionally found in the normal colon in small numbers; their number may increase in cer

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