Figure 1410

Electron micrograph of a Langerhans' cell. The nucleus (N) of a Langerhans' cell is characteristically indented in many places, and the cytoplasm contains distinctive rod-shaped bodies (arrows). Note the presence of tonofilaments (T) in adjacent keratinocytes (K) but the absence of these filaments in the Langerhans' cell, x 19,000. Inset. Pho tomicrograph of the epidermis shows the distribution and dendritic nature of the Langerhans' cells that were stained via immunostaining techniques with antibodies against CD1 a surface antigen. x300. (From Urmacher CD. In: Sternberg SS, ed. Histology for Pathologists. Philadelphia: Lippincott-Raven, 1997.)

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