Inheritance patterns

Here again, the picture is complex and confusing. Established techniques of genetic mapping have demonstrated that the patterns of inheritance differ between families. In some family trees, it looks as though a single gene might be responsible, although it is not expressed to full effect in every individual carrying it (so-called incomplete penetrance). In other pedigrees, however, the pattern is better fitted by smaller contributions from a number of different genes.

So far, therefore, it has not been possible to pinpoint one particular gene on one particular chromosome as the genetic key to the condition, either with traditional genetic mapping techniques or with more recent genome sequencing.

0 0

Post a comment