Key Terms h

Anticonvulsant drugs—Medications that relieve 3

or prevent seizures. g s

Arteriosclerosis—A thickening, hardening, and loss of elasticity of the walls of the arteries.

Attention-deficit disorder—A condition that mostly affects children and involves the inability to concentrate on various tasks.

Congenital—Present at birth.

Glaucoma—A group of eye diseases characterized by increased pressure within the eye significant enough to damage eye tissue and structures. If untreated, glaucoma results in blindness.

MAO inhibitors—A group of antidepressant drugs that decreases the activity of monoamine oxidase, a neurotransmitter found in the brain that affects mood.

Tic—A sudden involuntary behavior that is difficult or impossible for the person to suppress. Tics may be either motor (related to movement) or vocal, and may become more pronounced under stress.

Tourette's syndrome—Neurological disorder characterized by multiple involuntary movements and uncontrollable vocalizations called tics that come and go over years, usually beginning in childhood and becoming chronic. Sometimes the tics include inappropriate language.

Tricyclic antidepressants—Antidepressant medications that have the common characteristic of a three-ring nucleus in their chemical structure. Imipramine and amitriptyline are examples of tricyclic antidepressants.

The combination of amphetamines and antacids slows down the ability of the body to eliminate the amphetamine. Furazolidone (Furoxone) combined with amphetamine can significantly increase blood pressure. Sodium bicarbonate can reduce the amount of amphetamine eliminated from the body and dangerously increase amphetamine levels in the body. Certain medications taken to control high blood pressure, including guanadrel (Hylorel) and guanethidine (Ismelin), MAO inhibitors, and selegiline (Eldepryl) should not be used in conjunction with amphetamines. In addition, tricyclic antidepressants [including desipramine (Norpramin) and imipramine (Tofranil)],

S£ antihistamines, and anticonvulsant drugs should not be

"g combined with amphetamines. o

™ See also Attention-deficit/hyperactivity disorder; Tic d disorders <u

<u Resources

M Consumer Reports staff. Consumer Reports Complete Drug c Reference. 2002 ed. Denver: Micromedex Thomson

£ Healthcare, 2001.

"5 Ellsworth, Allan J. and others. Mosby's Medical Drug Ü Reference, 2001-2002. St. Louis: Mosby, 2001.

Hardman, Joel G. and Lee E. Limbird, eds. Goodman & Oilman's The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill, 2001. Mosby's GenRx Staff. Mosby's GenRx. 9th ed. St. Louis: Mosby, 1999.

Venes, Donald and Clayton L. Thomas. Taber's Cyclopedic Medical Dictionary. 19th ed. Philadelphia: F. A. Davis, 2001.

Mark Mitchell, M.D.

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