The IUCN lists 669 species of rodents under varying degrees of threat and endangerment. Thirty-two species from 23 genera are considered Extinct, and 22 of these extinct species occurred on either Oceanic islands or islands in the Caribbean. Causes of extinction relate primarily to loss of habitat and the introduction of feral predators. Ninety-five species of rodents are listed as Endangered throughout the world, with three species in the squirrel family Sciuridae considered Endangered in North America. Vulnerable and Lower Risk species number 166 each.

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