Conservation status

All heptaxodontid species are considered extinct. The presence of remains of some species among human refuse and artifacts suggests that they were hunted as food by Native Americans, who began settling the Antilles in 7000 B.C. Clidomys and Amblyrhiza probably became extinct long before the Native American colonization.

Some living heptaxodontids were probably present when the first Europeans began settling the West Indies in A.D. 1500. Early Spanish explorers briefly described an animal slightly larger than a hutia (Capromyidae) that was a source of food for the aboriginals, who called the creature "quemi," and which may have been a heptaxodontid.

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