Coronary MRA Receiver Operator Characteristics ROC Analysis

Magnetic resonance imaging (MRI) was evaluated as a potential noninvasive diagnostic tool to detect coronary artery bypass graft stenosis, in detecting stenotic grafts, including recipient vessels. Coronary angiography with baseline and stress flow mapping was performed. Marginal logistic regression was used to predict the probability for the presence of stenosis per graft type using multiple MRI variables. Receiver operator characteristics (ROC) analysis showed the diagnostic value of MRI. Sensitivity/specificity in detecting single vein grafts with stenosis > or = 50% and > or = 70% were significant. MRI with flow mapping was useful for identifying grafts and recipient vessels with flow-limiting stenosis. This proof-of-concept study suggested that noninvasive MRI detection of stenotic grafts in patients who present with recurrent chest pain after graft may be useful in selecting those in need of an invasive procedure [27].

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