By virtue of greater signal intensity, susceptibility artefacts and chemical shift, 3.0 T MR imagers with advanced techniques have provided promising results for the study of PD that could not be obtained with standard magnets. Microstructural, metabolic and functional data will, as never before, contribute to the early diagnosis and follow-up of PD.

Control subject

Fig. 16.5. fMRI with motor task (Siemens Allegra, 3.0 T). Hyperactivation of contralateral SMA, primary sensorimotor and pre-motor areas in a PD patient receiving dopaminergic therapy compared with a control subject

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