We have described the main MR tractographic techniques, which enable in vivo and non-invasive reconstruction of the anatomy of axon fibres, documenting the connections among grey matter areas. Tractography is the natural complement of functional MR, which can depict the activation of these areas. Combined use of these techniques is expected to be performed with increasing frequency in the future [80, 83, 99,100], and to yield useful results in the study of physiological and pathological CNS mechanisms, enabling better planning and quantification of therapeutic interventions.

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