The peripheral location of most prostate cancers is ideal for transrectal sampling. This may be guided by suspicious US appearances (peripheral hypoechoic areas) or represent random, multiple biopsies. Ten biopsies (five from each lobe) provides a high diagnostic yield. Any patient with a suspicious DRE or serum PSA level should be biopsied even if TRUS appearances are normal. If random, the biopsies should be carefully labelled to direct further biopsies in the event of a non-diagnostic histology report. Biopsies are obtained in such a way as to maximise sampling of the peripheral zone in each sector sampled.
Was this article helpful?