Squamous Cell Carcinoma

• histology suptype: classical/spindle cell/acantholytic/verrucous/desmoplastic/other.

• differentiation: grade I (over 75% differentiated).

- grade II (between 25 and 75% differentiated).

- grade III (under 75% differentiated).

- grade IV (no differentiation).

- lymphatic/vascular invasion: yes/no/uncertain.

- perineural invasion: yes/no/uncertain.

• excision margins:

- nearest peripheral: clear (mm)/involved (in situ/invasive).

- nearest deep: clear (mm)/involved (in situ/invasive).

• extent of local tumour spread:

- pTis carcinoma in situ.

- pT1 tumour < 20 mm in greatest dimension.

- pT3 tumour > 50 mm in greatest dimension.

- pT4 tumour invades extradermal structures (cartilage, skeletal muscle, bone).

- pN0 no regional lymph node metastasis.

- pN1 regional lymph node metastasis.

• Clarke levels - I (intraepidermal), II (papillary dermis), III (papillary-reticular interface), IV (reticular dermis), V (subcutaneous fat)

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