Specimen

• most prostate resections are retropubic radical prostatectomy specimens (including seminal vesicles) for biopsy-proven adenocarcinoma.

• occasionally, simple (retropubic/suprapubic) prostatectomy is performed for BPH. This is an enucleation procedure and usually produces an intact nodule with a wedge-shaped cut in one side. Orientation is not usually possible, although two distinct lobes should be identifiable. The specimen is weighed and measured (three dimensions, mm), then serially sectioned at 3-4 mm intervals. These sections are carefully examined for areas suspicious of carcinoma (yellow, firm) and six to eight cassettes of tissue processed, labelling the two lobes separately.

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