Femoral heads or large chunks of bone require adequate fixation and are then cut coronally with a junior hacksaw or vibrating table saw. The thin, sawn slices are placed in 10% formic acid for decalcification. The decalcified slices are then serially blocked, labelled and submitted in toto.
Amputation specimens are examined to:
• evaluate the resection margins including vessel involvement.
• determine the extent of bone involvement.
• evaluate the tumour necrosis, a measure of response to prior chemotherapy.
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