Initial Procedure

For partial resection

• weight (g) and measurements (cm) in each dimension.

• identify the capsular and cut parenchymal surfaces - the latter constitutes the surgical margin. Further orientation can only be given if marked appropriately by the submitting surgeon.

• paint the surgical margin and any areas of capsular bulging, retraction or reaction that might be related to an underlying mass lesion.

• serially section the liver perpendicular to the parenchymal resection margin at 0.5 cm intervals (Figure 9.3).

Plane of serial sections perpendicular to the resection margin

Painted parenchymal resection margin

Peritonealised capsule

Lay the slice flat on the bench for selection of perpendicular blocks surgical margin

Peritonealised capsule

Lay the slice flat on the bench for selection of perpendicular blocks

Plane of serial sections perpendicular to the resection margin

Nonlesional liver and capsule

Tumour and liver capsule

Nonlesional liver and capsule surgical margin

Painted parenchymal resection margin

Sample representative blocks of tumour and its relationships to capsule, surgical margin and veins.

Sample the nonlesional liver.

Figure 9.3. Partial hepatectomy specimen.

• fixation by laying flat and immersion in 10% formalin for 36-48 hours.

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