Initial Procedure

• if intact, orientate the specimen and ink its margins.

• otherwise, if a larger specimen is submitted, ink its margins. A line of ink drawn across medium-sized fragments can aid orientation after microscopic examination and assist assessment of margins.

• slice the larger pieces into 0.4 cm-thick slices transversely, using a band saw or equivalent.

• measurements:

- if fragmented, number of fragments, total weight (g) and dimensions of largest specimen (cm).

- number of fragments consisting of tumour.

- distance to closest surgical margins (cm).

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