Histopathology report

Final reports of laryngectomy specimens should include details on:

• the specimen type

• the type of tumour present:

- squamous cell carcinoma NOS.

- SCC variants include basaloid, adenosquamous, spindle cell, verrucous adenocarcinoma (salivary gland types).

- neuroendocrine carcinomas.

Hyoid bone — Pre-epiglottic space

Thyroid cartliage

Hyoid bone — Pre-epiglottic space

Thyroid cartliage

Cricoid

Epiglottis

Outline of supraglottic carcinoma spreading into pre-epiglottic and subglottic spaces

Cricoid a

Per-commissural spread to left cord

Left thyroid lamina

Left arytenoid cartilage

Glottis Cricoid cartilage

Midline Section a-b

Extralaryngeal involvement

Closest laryngeal mucosal limit in right pyriform fossa

Extralaryngeal muscles

Extralaryngeal involvement

Closest laryngeal mucosal limit in right pyriform fossa

Paraglottic space involvement b

Figure 15.4. Laryngectomy for supraglottic carcinoma with transglottic and extralaryngeal spread. Suggested siting and orientation of tissue blocks for laryngectomy specimen. (a) View from right lateral aspect. (b) Slice through vocal cords viewed from above.

• the grade of tumour assessed at the invasive front.

• cohesive or non-cohesive patterns (more metastasis with non-cohesive).

• the extent of local spread.

• the distance of tumour from the nearest mucosal margin.

• the distance of the tumour from the nearest deep margin.

• intravascular and/or perineural spread.

• involvement of perilaryngeal lymph nodes.

• other pathology such as dysplasia or radiation injury.

If other specimens are attached as an in-continuity dissection (e.g., neck dissection, thyroid gland, oesophagus, skin, etc.), these can be cut separately in the usual fashion.

0 0

Post a comment