Histopathology report

• tumour type - anal canal squamous carcinoma/other.

• tumour differentiation - basaloid/keratinising/non-keratinising/ductular component.

• tumour edge - pushing/infiltrative/lymphoid response.

• extent of local tumour spread

- pTis carcinoma in situ.

- pT1 tumour < 2 cm in greatest dimension.

- pT2 2 cm < tumour < 5 cm in greatest dimension.

- pT3 tumour > 5 cm in greatest dimension.

- pT4 tumour of any size invading adjacent organ(s), e.g., vagina, urethra, bladder.

• lymphovascular invasion - present/not present.

- anal margin/perianal skin lesions: inguinal nodes.

- anal canal lesions: perirectal, internal iliac, inguinal nodes in that order.

- pN0 no regional lymph node mestastasis.

- pN1 metastasis in perirectal lymph node(s).

- pN2 metastasis in unilateral internal iliac and/or unilateral inguinal lymph node(s).

- pN3 metastasis in perirectal and inguinal lymph nodes and/or bilateral internal iliac and/or bilateral inguinal lymph nodes.

• excision margins

- proximal rectal and distal perianal/perineal limits of tumour clearance (cm).

- deep circumferential radial margin of clearance (mm).

• other pathology

- Condylomatous warts or giant condyloma, Bowen's disease, anal fistula, Crohn's disease, AIN, radio-/chemotherapy necrosis and tumour regression.

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