Histopathology Report

• non-neoplastic

- inflammation: acute/chronic/xanthogranulomatous.

- necrosis/perforation/abscess/empyema/fistula.

- mucocoele.

• tumour type - adenocarcinoma/other.

• tumour differentiation - well/moderate/poor.

• tumour edge - pushing/infiltrative/lymphoid response.

• extent of local tumour spread.

- pTis carcinoma in-situ.

- pT1 tumour limited to gall bladder wall:

- a. lamina propria.

- pT2 tumour invades perimuscular connective tissue, no extension beyond serosa or into liver.

- pT3 tumour perforates serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, e.g., stomach, duodenum, colon, pancreas, omentum, extrahepatic bile ducts.

- pT4 tumour invades main portal vein or hepatic artery, or invades two or more extra hepatic organs or structures.

• lymphovascular invasion - present/not present. Note perineural invasion.

• regional lymph nodes:

- cystic duct node, pericholedochal, hilar, peripancreatic (head only), periduodenal, periportal, coeliac and superior mesenteric nodes.

- pN0 no regional lymph node mestastasis.

- pN1 regional lymph node metastasis.

• excision margins:

- cystic duct limit of tumour and mucosal dysplasia clearance (mm)

- adventitial margin of tumour clearance (mm)

- hepatic and common bile duct margins of tumour clearance (mm).

• other pathology:

- calculi, sclerosing cholangitis.

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