Blocks for histology Figure 302

• sample proximal (base) and distal (apical) margins as described.

• sample the seminal vesicles at their bases (junction with the prostate) and the vasa deferentia at their limits.

• each serial section is bisected into right and left halves (and if necessary into superior and inferior quadrants) to fit into routine cassettes and the entire gland processed for histological examination, labelling each block carefully to aid microscopic interpretation.

• alternatively, some pathologists prefer to partially sample the prostate initially, concentrating on suspicious areas and random sections from the circumferential margin.

• whole mount sectioning may be available in some centres, greatly facilitating histological interpretation, but is usually reserved for teaching and research purposes.

• all pelvic lymph nodes (usually submitted separately) should be counted and sampled.

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