Biopsy Specimens

Small biopsies are promptly put into 10% formalin fixative.

Endobronchial/ transbronchial biopsies

• count the number of fragments.

• record the greatest dimension of the largest fragment (mm).

• note the colour and consistency of the fragments.

• place the fragments in cassettes between foam pads or wrapped in filter paper or in molten agar for processing.

• cut through multiple levels, keeping intervening spares for further stains.

Open lung biopsy

• reinflate lung using a formalin injection.

• record the size (cm) and weight (g)/number of fragments.

• describe the colour and consistency.

• serially transverse section at 3 mm intervals and sample representative blocks.

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