Biopsy Specimens

Tiny pieces of tissue (several mm) retrieved using either "cold" cup forceps or a small diathermy loop are counted, measured, processed intact and examined histologically through three levels. TURB specimens contain larger fragments possibly recognisable as papillary tumour grossly. These are weighed collectively and all tissue embedded if possible. If sampling is required, at least six blocks are processed, concentrating on more solid tissue and fragments containing identifiable muscle. It will not normally be feasible to orientate such fragments. Tissue from the tumour base may be submitted separately.

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