Natural Lipoma Lumps Cure and Treatment
Benign tumours squamous cell papilloma commonly occurs on the lips, cheeks and tongue and is often associated with viral warts on the hands. Neurilemmoma, neurofibroma and the granular cell tumour are not infrequently encountered. Lipoma presents as a mucosal polyp, clinically similar to a fibroepithelial polyp. Benign tumours of salivary gland origin arise in the upper lip and in the palate, usually at the junction between the hard and soft palates, the commonest of which is the pleomorphic adenoma. Benign salivary tumours are rare in the tongue and floor of mouth most salivary tumours in the lower parts of the oral cavity are adenocarcinomas.
Lipomas Localized fat accumulations include single lipomas, multiple lipomas, liposarcomas, and lipodystrophy (2). Lipomas vary in size from 1 cm to 15 cm. They can occur in any body region, and represent encapsulated accumulations of fat. Multiple lipomatosis is an inherited disease transmitted as an autosomal-dominant trait. Von Recklinghausen's syndrome, Maffucci's syndrome, and Madelung's deformity are lipomatous syndromes. Liposarcomas are relatively rare, representing
The mucocutaneous manifestations of CS are the most common, yet the most difficult to recognize, with an estimated penetrance of 99 by the end of the third decade (17). The characteristic skin lesions of CS are trichilemmomas and papillomatous papules (25). Trichilemmomas are hamartomas of the infundibulum of the hair follicle and are characteristically found at or near the hairline while papillomatous papules are condyloma-like lesions occurring frequently on the face, hands, feet, or oral mucosa. It is not uncommon to see papillomatous papules proliferate at pressure points particularly on the palmar and plantar surfaces. Additional cutaneous manifestations include acral keratoses, small punctate lesions commonly seen on the palmar surface of the hands, which are often associated with a central depression or pit. Lipomas are a feature, but are seen more commonly in BRRS (14). Patients appear predisposed to excessive scarring, even cheloid formation, at the site of traumatic or...
Liposarcoma arising within the retroperitoneal fat, well-differentiated liposarcoma, particularly the sclerosing subtype, represents one of the commonest histological subtypes. There is a very low risk of metastasis with this type of lesion, which indeed has been described as an atypical lipoma at other sites. However, such lesions can be difficult to excise from the retroperi-toneum and may prove lethal because of pressure effects on adjacent organs or local recurrence if incompletely excised. These tumours may also contain or develop a dedifferentiated spindle cell component, resembling a high-grade spindle cell sarcoma. Careful macroscopic examination and adequate sampling are important. Lipomas also arise at this site careful evaluation is necessary to distinguish from well-differentiated liposarcoma as described above.
Skin signs varies from 4 to 75 years of age. The most frequently found cutaneous lesions are facial papules, which present as skin-colored or yellowish-tan verrucous papules that can resemble common warts and histologically reveal trichilemmomas or nonspecific hair follicle proliferations. These papules can be very numerous and can coalesce around facial orifices and ears (Fig. 1). The oral lesions present as 1 to 3 mm skin-colored papules, which can coalesce to form a characteristic cobblestone pattern (Fig. 2), or can be so extensive that they involve the entire oral cavity, including the tongue. Involvement of the mucosa is seen in over 80 of patients and usually follows the development of the facial lesions. Other cutaneous findings in CS include lipomas, hemangiomas, xanthomas, vitiligo, neuromas, cafe-au-lait spots, periorificial and acral lentigines, and acanthosis nigricans (2).
Benign tumors of the small bowel include leiomyomas, adenomas which are common in the duodenum of familial adenomatous polyposis (FAP) patients , lipomas, hamartomatous polyps (such as those in Peutz-Jeghers and to a lesser degree, juvenile polyposis syndrome), and other miscellaneous lesions (fibroma, ganglioneuromas, neurofibroma, hemangioma, lymphangi-oma) (1). Surgery is indicated for most symptomatic tumors with simple excision being sufficient treatment. However, villous adenomas of the small intestine have a definite potential for malignant degeneration with estimates ranging from 35 to 58 with the incidence being greatest in those lesions 4 cm (1). These lesions most commonly occur in the duodenum, yet only account for about 1 of all duodenal tumors (1).
Miscellaneous conditions chronic adrenalitis is usually secondary to inflammation in adjacent organs, e.g., chronic pyelonephritis adrenal haemorrhage (secondary to sepsis, shock, coagulopathy), cysts, myelolipoma (composed of fat and heamatopoietic tissue), lipoma, angioma, schwannoma and adenomatoid tumour (of mesothelial origin) are all occasionally encountered in surgical pathology practice.
The study of the numerous varieties of benign and malignant adipose tissue tumors provides further insight into, and confirmation of, the sequence of adipose tissue differentiation described above. Adipose tissue tumors are classified by the morphology of the predominant cell In the tumor (Fig. 6.5). As with epithelial tumors and tumors of fibroblast origin, the variety of adipose tissue tumors reflects the normal pattern of adipose tissue differentiation. That is, discrete tumor types can be described that consist primarily of cells resembling a given stage in adipose tissue differentiation. The most common adipose tissue tumor is the lipoma. It is more common than all other soft tissue tumors combined. Lipomas are usually found in subcutaneous tissues in middle-aged and elderly individuals. Although Figure 6.5 relates primarily to white adipose tissue tumors, tumors of brown adipose tissue are also found. Not surprisingly, these are called hibernomas.
Pineal region tumors encompass a large group of neoplasms, with quite variable histology and malignant potential (see Table 32.1) 7-12 . The most common tumors are of germ cell origin (60 per cent) and include germinoma, teratoma, choriocarcinoma, embryonal carcinoma, and yolk sac tumors. Primary neuroectodermal tumors comprise 15 per cent of pineal region malignancies and include astrocytoma, oligodendroglioma, ependymoma, and other less common histologies. Pineal parenchymal tumors account for 15 per cent of neoplasms in this region, while primary non-neuroectodermal and miscellaneous tumors (e.g., lipoma, meningioma, and metastases) comprise the remaining 10 per cent of the cases. Primary Non-Neuroectodermal Tumors (5 per cent) Lipoma Hemangioma Meningioma Hemangiopericytoma Craniopharyngioma Choroids plexus papilloma Miscellaneous (5 per cent) Pineal cyst Arachnoid cyst Epidermoid cyst Dermoid cyst Metastatic tumors
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