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Al-Regaiey, K.A., Masternak, M.M., Bonkowski, M., Sun, L., and Bartke, A. (2005). Long-lived growth hormone receptor knockout mice: Interaction of reduced insulinlike growth factor 1/insulin signaling and caloric restriction. Endocrinology 146, 851-860.

Bartke, A. (1965). Influence of luteotrophin on fertility of dwarf mice. J. Reprod. Fertil. 10, 93-103.

Bartke, A. (1979a). Genetic models in the study of anterior pituitary hormones. In Genetic Variation in Hormone Systems,, Shire, J.G.M. (ed). Boca Raton: CRC Press, pp. 113-126.

Bartke, A. (1979b). Prolactin-deficient mice. In Animal Models for Research on Contraception and Fertility. Alexander, N.J. (ed). Hagerstown: Harper & Row, pp. 360-365.

Bartke, A. (2000). Delayed aging in Ames dwarf mice. Relationships to endocrine function and body size. In The Molecular Genetics ofAging. Vol. 29. Hekimi, S. (ed). Berlin, Heidelberg: Springer-Verlag, pp. 181-202.

Bartke, A., Coschigano, K., Kopchick, J., Chandrashekar, V., Mattison, J., Kinney, B., and Hauck, S. (2001a). Genes that prolong life: Relationships of growth hormone and growth to aging and lifespan. J. Gerontol.: Biol. Sci. 56A, B340-B349.

Bartke, A., Wright, J.C., Mattison, J., Ingram, D.K., Miller, R.A., and Roth, G.S. (2001b). Extending the lifespan of long-lived mice. Nature 414, 412.

Bartke, A., Chandrashekar, V., Bailey, B., Zaczek, D., and Turyn, D. (2002). Consequences of growth hormone (GH) overexpression and GH resistance. Neuropeptides 36, 201-208.

Bartke, A. (2003). Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice. Neuroendocrinology 78, 210-216.

Bartke, A., and Brown-Borg, H. (2004). Life extension in the dwarf mouse. Curr Top Developmental Biology 63, 189-225.

Bartke, A., Peluso, M.R., Moretz, N., Wright, C., Bonkowski, M., Winters, T.A., et al. (2004). Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice. Horm. Metab. Res. 36, 550-558.

Baynes, J.W., and Monnier, V.M. (1989). The Maillard Reaction in Aging, Diabetes and Nutrition. New York: Alan R. Liss.

Berryman, D.E., List, E.O., Coschigano, K.T., Behar, K., Kim, J.K., and Kopchick, J.J. (2004). Comparing adiposity profiles in three mouse models with altered GH signaling. Growth Hormone & IGF Research 14, 309-318. Besson, A., Salemi, S., Gallati, S., Jenal, A., Horn, R., Mullis, P.S., and Mullis, P.E. (2003). Reduced longevity in untreated patients with isolated growth hormone deficiency. J. Clin. Endocrinol. Metab. 88, 3664-3667. Borg, K.E., Brown-Borg, H.M., and Bartke, A. (1995). Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse. Proc. Soc. Exp. Biol. Med. 210, 126-133. Boylston, W.H., Gerstner, A., DeFord, J.H., Madsen, M., Flurkey, K., Harrison, D.E., and Papaconstantinou, J. (2004). Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. Aging Cell 3, 283-296. Brown-Borg, H.M., Borg, K.E., Meliska, C.J., and Bartke, A.

(1996). Dwarf mice and the ageing process. Nature 384, 33. Brown-Borg, H.M., and Rakoczy, S.G. (2000). Catalase expression in delayed and premature aging mouse models. Exp. Gerontol. 35, 199-212. Brown-Borg, H., Johnson, W., Rakoczky, S., and Romanick, M. (2001). Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice. Amer. Aging Assoc. 24, 85-96. Brown-Borg, H.M., and Rakoczy, S.G. (2005). Glutathione metabolism in long-living Ames dwarf mice. Exp. Gerontol. 40, 115-120.

Carsner, R.L., and Rennels, E.G. (1960). Primary site of gene action in anterior pituitary dwarf mice. Science 18:131:829. Chandrashekar, V., Zaczek, D., and Bartke, A. (2004). The consequences of altered somatotropic system on reproduction. Biol. Reprod. 71, 17-27. Chandrashekar, V., Bartke, A., Coschigano, K.T., and Kopchick, J.J. (1999). Pituitary and testicular function in growth hormone receptor gene knockout mice. Endocrinology

140, 1082-1088.

Cheng, C.M., Mervis, R.F., Niu, S.L., Salem, N., Witters, L.A., Tseng, V., et al. (2003). Insulin-like growth factor 1 is essential for normal dendritic growth. Journal of Neuroscience Research 73, 1-9. Clayton, R.N. (2003). Cardiovascular function in acromegaly.

Endocr. Rev. 24, 272-277. Coschigano, K.T., Clemmons, D., Bellush, L.L., and Kopchick, J.J. (2000). Assessment of growth parameters and lifespan of GHR/BP gene-disrupted mice. Endocrinology

141, 2608-2613.

Coschigano, K.T., Holland, A.N., Riders, M.E., List, E.O., Flyvbjerg, A., and Kopchick, J.J. (2003). Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased lifespan. Endocrinology 144, 3799-3810.

Dolle, M.E.T., Snyder, W.K., and Vijg, J. (2001). Genotyping the Prop-1 mutation in Ames dwarf mice. Mech. Ageing Dev. 122, 1915-1918.

Dominici, F.P., Arostegui Diaz, G., Bartke, A., Kopchick, J.J., and Turyn, D. (2000). Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. J. Endocrinol. 166, 579-590.

Dominici, F.P., Hauck, S., Argentino, D.P., Bartke, A., and Turyn, D. (2002). Increased insulin sensitivity and upregula-tion of insulin receptor, insulin receptor substrate (IRS)-I and IRS-2 in liver of Ames dwarf mice. J. Endocrinol. 173, 81-94.

Dominici, F.P., Argentino, D.P., Bartke, A., and Turyn, D. (2003). The dwarf mutation decreases high dose insulin responses in skeletal muscle, the opposite of effects in liver. Mech. Ageing Dev. 124, 819-827.

Eicher, E., and Beamer, W. (1980). New mouse dw allele: Genetic location and effects on lifespan and growth hormone levels. Journal Heredity May-Jun; 71, 187-190.

Eigenmann, J.E., Amador, A., and Patterson, D.F. (1988). Insulin-like growth factor I levels in proportionate dogs, chondrodystrophic dogs and in giant dogs. Acta Endocrinol. 118, 105-108.

Facchini, F.S., Hua, N., Abbasi, F., and Reaven, G.M. (2001). Insulin resistance as a predictor of age-related diseases. J. Clin. Endocrinol. Metab. 86, 3574-3578.

Fabris, N., Pierpaoli, W., and Sorkin, E. (1972). Lymphocytes, hormones, and ageing. Nature 240, 557-559.

Flurkey, K., Papaconstantinou, J., Miller, R.A., and Harrison, D.E. (2001). Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Nat. Acad. Sci., USA 98, 6736-6741.

Gruneberg, H. (1952). The Genetics of the Mouse. Martinus Nijhoff, The Hague, pp. 122-129.

Guarente, L., and Kenyon, C. (2000). Genetic pathways that regulate ageing in model organisms. Nature 408, 255-262.

Gussekloo, J., van Exel, E., de Craen, A.J., Meinders, A.E., Frolich, M., and Westendorp, R.G. (2005). Thyroid status, performance, and survival in old age. JAMA 292, 2591-2599.

Hauck, S.J., Hunter, W.S., Danilovich, N., Kopchick, J.J., and Bartke, A. (2001). Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse. Exp. Biol. Med. 226, 552-558.

Hauck, S.J., Aaron, J.M., Wright, C., Kopchick, J.J., and Bartke, A. (2002). Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm. Metab. Res. 481-486.

Heiman, M., Tinsley, F., Mattison, J., Hauck, S., and Bartke, A. (2003). Body composition of prolactin-, growth hormone-, and thyrotropin-deficient Ames dwarf mice. Endocrine 20, 149-154.

Holzenberger, M., Dupont, J., Ducos, B., Leneuve, P., Geloen, A., Evens, P., Cervera, P., and LeBouc, Y. (2003). IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421, 182-187.

Hsieh, C.C., DeFord, J.H., Flurkey, K., Harrison, D.E., and Papaconstantinou, J. (2002). Effects of the Pit 1 mutation on the insulin signaling pathway: Implications on the longevity of the long-lived Snell dwarf mouse. Mech. Ageing Dev. 123, 1244-1255.

Hsieh, C.-C., and Papaconstantinou, J. (2004). Akt/PKB and p38 MAPK signaling, translational initiation and longevity in Snell dwarf mouse livers. Mech. Ageing Dev. 125, 785-798.

Hunter, W.S., Croson, W.B., Bartke, A., Gentry, M.V., and Meliska, C.J. (1999). Low body temperature in long-lived Ames dwarf mice at rest and during stress. Physiol. Behav. 67, 433-437.

Ikeno, Y., Bronson, R.T, Hubbard, G.B, Lee, S, Bartke, A. (2003). Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: Correlation to extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 58A, 291-296.

Jazwinski, S.M. (1996). Longevity, genes, and aging. Science 273, 54-59.

Khaw, K.T., Wareham, N., Bingham, S., Luben, R., Welch, A., and Day, N. (2004). Association of hemoglobin A1c with cardiovascular disease and mortality in adults: The European prospective investigation into cancer in Norfolk. Ann. Intern. Med. 141, 413-420.

Kimura, K.D., Tissenbaum, H.A., Liu, Y., and Ruvkun, G. (1997). daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946.

Kinney, B.A., Meliska, C.J., Steger, R.W., and Bartke, A. (2001a). Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. Horm. Behav. 39, 277-284.

Kinney, B.A., Coschigano, K.T., Kopchick, J.J., and Bartke, A. (2001b). Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol. Behav. 72, 653-660.

Kinney-Forshee, B., Kinney, N., Steger, R., and Bartke, A. (2004). Could a deficiency in growth hormone signaling be beneficial to the aging brain? Physiol. Behav. 80, 589-594.

Krzisnik, C., Kolacio, Z., Battelino, T., Brown, M., Parks, J.S., and Laron, Z. (1999). The ''Little People'' of the island of Krk—revisited. Etiology of hypopituitarism revealed. The Journal of Endocrine Genetics 1, 9-19.

Lambert, A.J., Wang, B., and Merry, B.J. (2004). Exogenous insulin can reverse the effects of caloric restriction on mitochondria. Biochemical and Biophysical Research Communications 316, 1196-1201.

Laron, Z. (2005). Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity? Mech. Ageing Dev. 126, 305-307.

Li, S., Crenshaw, B.E., Rawson, E.J., Simmons, D.M., Swanson, L.W., and Rosenfeld, M.G. (1990). Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347, 528-533.

Liu, J.-L., Coschigano, K.T., Robertson, K., Lipsett, M., Guo, Y., Kopchick, J.J., Kumar, U., and Liu, Y.L. (2004). Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. Am. J. Physiol. Endocrinol. Metab. 287, E405-413.

Lupu, F., Terwilliger, J.D., Lee, K., Segre, G.V., and Efstratiadis, A. (2001). Roles of growth hormone and insulin-like growth factor I in mouse postnatal growth. Develop. Biol. 229, 141-162.

Masoro, E.J. (2001). Dietary restriction: An experimental approach to the study of the biology of aging. In Handbook of the Biology of Aging (5th ed.). Masoro, E.J. and Austad, S.N. (eds). San Diego: Academic Press, pp. 396-420.

Masternak, M., Al-Regaiey, K., Bonkowski, M., Panici, J., Sun, L., Wang, J., et al. (2004). Divergent effects of caloric restriction on gene expression in normal and long-lived mice. Journal of Gerontology: A Biol. Sci. Med. Sci. 59, 784-788.

Miller, R.A., Harper, J.M., Galecki, A., and Burke, D.T. (2002). Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 1, 22-29.

Miskin, R., and Masos, T. (1997). Transgenic mice overexpres-sing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity. J. Gerontol. 52A, B118-B124.

Murakami, S., Salmon, A., and Miller, R. (2003). Multiplex stress resistance in cells from long-lived dwarf mice. FASEB 17, 1565-1566.

Ooka, H., Fujita, S., and Yoshimoto, E. (1983). Pituitary-thyroid activity and longevity in neonatally thyroxine-treated rats. Mech. Ageing Dev. 22, 113-120.

Parr, T. (1996). Insulin exposure controls the rate of mammalian aging. Mech. Ageing Dev. 88, 75-82.

Parsons, J.A., Bartke, A., and Sorenson, R.L. (1995). Number and size of islets of langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: Effect of lactogenic hormones. Endocrinology 136, 2013-2021.

Partridge, L., Gems, D., and Withers, D.J. (2005). Sex and death: What is the connection? Cell 120, 461-472.

Patronek, G.J., Waters, D.J., and Glickman, L.T. (1997). Comparative longevity of pet dogs and humans: Implications for gerontology research. J. Gerontol. 52A, B171-B178.

Phelps, C.J. (2004). Postnatal regression of hypothalamic dopaminergic neurons in prolactin-deficient snell dwarf mice. Endocrinology 145, 5656-5664.

Phillips, J.P., Parkes, T.L., and Hilliker, A.J. (2000). Targeted neuronal gene expression and longevity in Drosophila. Exp. Gerontol. 35, 1157-1164.

Rodgers, J.T., Lerin, C., Haas, W., Gygi, S.P., Spiegelman, B.M., and Puigserver, P. (2005). Nutrient control of glucose homeostasis through a complex of PGC-1[alpha] and SIRT1. Nature 434, 113-118.

Rollo, C.D. (2002). Growth negatively impacts the lifespan of mammals. Evol. Dev. 4, 55-61.

Rosen, T., and Bengtsson, B.A. (1990). Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 336, 285-288.

Rosen, C.J., and Pollak, M. (1999). IGF-I and aging: A new perspective for a new century. Trends Endocrinol. Metab. 10, 136-142.

Salmon, A.B., Murakami, S., Bartke, A., Kopchick, J., Yasumura, K., and Miller, R.A. (2005). Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am. J. Physiol. Endocrinol. Metab. 10, 1152.

Samaras, T., Elrick, H., and Storms, L. (2003). Is height related to longevity? Life Science 72, 1781-1802.

Sanz, A., Bartke, A., and Barja, G. (2002). Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain. J. Am. Aging Assoc. 25, 119-122.

Schaible, R., and Gowen, J.W. (1961). A new dwarf mouse. Genetics 46, 896.

Schneider, G.B. (1976). Immunological competence in Snell-Bagg pituitary dwarf mice: Response to the contact-sensitizing agent oxazolone. Am. J. Anat. 145, 371-394.

Shimokawa, I., Higami, Y., Utsuyama, M., Tuchiya, T., Komatsu, T., Chiba, T., and Yamaza, H. (2002). Lifespan extension by reduction of the growth hormone-insulinlike growth factor-1 axis: Relation to caloric restriction. Am. J. Pathol. 160, 2259-2265.

Shire, J.G.M. (1973) Growth hormone and premature ageing. Nature 245, 215-216.

Silberberg, R. (1972) Articular aging and osteoarthrosis in dwarf mice. Path. Miocrobiol. 38, 417-430.

Snell, G.D. (1929) Dwarf, a new mendelian recessive character of the house mouse. Proc. Natl. Acad. Sci. USA 15, 733-734.

Soares, M.J., Bartke, A., Colosi, P., and Talamantes, F. (1984) Identification of a placental lactogen in pregnant Snell and Ames dwarf mice. Soc. Exp. Biol. Med. 175, 106-108.

Sonntag, W.E., Carter, C.S., Ikeno, Y., Ekenstedt, K., Carlson, C.S., Loeser, R.F., et al. (2005) Adult-onset growth hormone and IGF-1 deficiency reduces neoplastic disease, modifies age-related pathology and increases lifespan. Endocrinology 146, 2920-2932.

Sornson, M.W., Wu, W., Dasen, J.S., Flynn, S.E., Norman, D.J., O'Connell, S.M., et al. (1996) Pituitary lineage determination by the prophet of pit-1 homeodomain factor defective in Ames dwarfism. Nature 384, 327-333.

Stauber, A.J., Brown-Borg, H., Liu, J., Waalkes, M.P., Laughter, A., Staben, R.A., et al. (2005) Constitutive expression of peroxisome proliferator-activated receptor a-regulated genes in dwarf mice. Mol. Pharmacol. 67, 681-694.

Sun, L.Y., Al-Regaiey, K., Masternak, M.M., Wang, J., and Bartke, A. (2005a) Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice. Neurobiol. Aging 26, 929-937.

Sun, L.Y., Evans, M.S., Hsieh, J., Panici, J., and Bartke, A. (2005b) Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice. Endocrinology 146, 1138-1144.

Tatar, M., Bartke, A., and Antebi, A. (2003) The endocrine regulation of aging by insulin-like signals. Science 299, 1346-1351.

Tretli, S. (1989) Height and weight in relation to breast cancer morbidity and mortality. A prospective study of 570,000 women in Norway. Int. J. Cancer 44, 23-30.

Tsuchiya, T., Dhahbi, J.M., Cui, X., Mote, P.L., Bartke, A., and Spindler, S.R. (2004) Additive regulation of hepatic gene expression by dwarfism and caloric restriction. Physiol. Genomics 17, 307-315.

van Heemst, D., Beekman, M., Mooijaart, S.P., Heijmans, B.T., Brandt, B.W., Zwaan, B.J., et al. (2005) Reduced insulin/ IGF-1 signaling and human longevity. Aging Cell 4, 79-85.

Vergara, M., Smith-Wheelock, M., Harper, J.M., Sigler, R., and Miller, R.A. (2004) Hormone-treated Snell dwarf mice regain fertility but remain long lived and disease resistant. J. Gerontol. A Biol. Sci. Med. Sci. 59, 1244-1250.

Ward, R.D., Raetzman, L.T., Suh, H., Stone, B.M., Nasonkin, I.O., and Camper, S.A. (2005) Role of PROP1 in pituitary gland growth. Mol. Endocrinol. 19, 698-710.

Wessells, R.J., Fitzgerald, E., Cypser, J.R., Tatar, M., and Bodmer, R. (2004) Insulin regulation of heart function in aging fruit flies. Nat. Genet. 36, 1275-1281.

Woods, K.A., Camacho-Hubner, C., Savage, M.O., and Clark, A.J.L. (1996) Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl. J. Med. 335, 1363-1367.

Yu, H., and Rohan, T. (2000) Role of the insulin-like growth factor family in cancer development and progression. Journal of National Cancer Inst. 20, 1472-1489.

Zhou, Y., Xu, B.C., Maheshwari, H.G., He, L., Reed, M., Lozykowski, M., et al. (1997) A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (The Laron mouse). 94, 13215-13220.

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