References

AGS Ethics Committee. Informed consent for research on human subjects with dementia. J Am Geriatr Soc. 1998;46:1308-1310.

Alzheimer's Association. Research consent for cognitively impaired adults: Recommendations for institutional review boards and investigators. Alzheimer Dis Assoc Discord. 2004;18:171-175.

American College of Physicians. Ethics manual, 5th ed. Ann Intern Med. 2005;142:560-582.

American Psychiatric Association. Guidelines for assessing the decision-making capacities of potential research subjects with cognitive impairment (1998). Available at: http://www.psych.org/edu/other_res/lib_archives/archives/ 199811.pdf

American Society of Human Genetics. Statement on informed consent for genetic research. Am J Hum Genet. 1996;59: 471-474.

Avorn J. Including elderly people in clinical trials. BMJ. 1997;315:1033-1034.

Banks DA and Fossel M. Telomeres, cancer, and aging: Altering the human life span. JAMA. 1997;278:1345-1348.

Bayer A and Tadd W. Unjustified exclusion of elderly people from studies submitted to research ethics committee for approval: Descriptive study. BMJ. 2000;321:992-993.

Beauchamp TL and Childress JF. Principles of Biomedical Ethics, 5th ed. (New York: Oxford University Press, 2001).

Beecher HK. Ethics and clinical research. New Engl J Med. 1966;274:1354-1360.

Bell JA, May FE, Stewart RB. Clinical research in the elderly: Ethical and methodological considerations. Drug Intell Clin Pharm. 1987;21:1002-1007.

The Belmont Report (1979). Ethical principles and guidelines for the protection of human subjects of research. Available at: http://www.hhs.gov/ohrp/humansubjects/ guidance/belmont.htm

Blacker D, Haines JL, Rodes L, Terwedow H, Go RCP, Harrell LE, et al. Neurology. 1997;48:139-147.

Bugeja G, Kumar A, Banerjee AK. Exclusion of elderly people from clinical research: A descriptive study of published reports. BMJ. 1997;315:1059.

Capron AM. Ethical and human-rights issues in research on mental disorders that may affect decision-making capacity. New Engl J Med. 1999;340:1430-1434.

Cassel CK. Research in nursing homes. J Am Geriatr Soc. 1985;33:795-799.

Cassel CK. Ethical issues in the conduct of research in long term care. Gerontologist. 1988;28:90-96.

Cohen JM. Top ten investigator responsibilities when conducting human subjects research. http://irb.mc.duke.edu/ppt/ investigator_top_ten-full-jeff_cohen-4-12-02.ppt

Denham MJ. The ethics of research in the elderly. Age and Aging. 1984;13:321-327.

Department of Health and Human Services. Protection of human subjects, 45 CFR 46. Available at: http://www.hhs.gov/ohrp/ humansubjects/guidance/45cfr46.htm

Dubler NN. Legal judgments and informed consent in geriatric research. J Am Geriatr Soc. 1987;35:545-549.

Flory J and Emanuel E. Interventions to improve research participants' understanding in informed consent for research: A systematic review. JAMA. 2004;292:1593-1601.

Hanson LC and Rodgman E. The use of living wills at the end of life: A national study. Arch Intern Med 1996;156:1018-1022.

Heiat A, Gross CP, Krumholtz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. Arch Intern Med. 2002;162:1682-1688.

High DM. Research with Alzheimer's disease subjects: Informed consent and proxy decision making. J Am Geriatr Soc. 1992;40:950-957.

Hutchins LF, Unger JM, Crowley JJ, Coltman CA, Albain KS. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. New Engl J Med. 1999;341:2061-2067.

Jahnigen DW and Schrier RW. The doctor/patient relationship in geriatric care. Clin Geriatr Med 1986;2:457-464.

Kapp MB. Proxy decision making in Alzheimer disease research: Durable powers of attorney, guardianship, and other alternatives. Alzheimer Disease Associated Disorders. 1994; 8(suppl):28-37.

Karlawish JHT. Research involving cognitively impaired adults. New Engl J Med. 2003;348:1389-1392.

Kaye JM, Lawton P, Kaye D. Attitudes of elderly people about clinical research on aging. The Gerontologist. 1990;30:100-106.

Lane LW, Cassel CK, Bennett W. Ethical aspects of research involving elderly subjects: Are we doing more than we say? J Clinical Ethics. 1990;1:278-285.

Leader MA and Neuwirth E. Clinical research and the noninstitutional elderly: A model for subject recruitment. J Am Geriatr Soc. 1978;26:27-31.

Lipsitz LA, Pluchino FC, Wright SM. Biomedical research in the nursing home: Methodological issues and subject recruitment results. J Am Geriatr Soc. 1987;35:629-634.

Longo VD and Finch CE. Genetics of aging and diseases: From rare mutations and model systems to disease prevention. Arch Neurol. 2002;59:1706-1708.

LoVerde ME, Prochazka AV, Byyny RL. Research consent forms: Continued unreadability and increasing length. J Gen Intern Med. 1989;4:410-412.

Marson DC, Schmitt FA, Ingram KK, Harrell LE. Determining the competency of Alzheimer patients to consent to treatment and research. Alzheimer Disease Associated Disorders. 1994;8(suppl):5-18.

Michels R. Are research ethics bad for our mental health? New Engl J Med. 1999;340:1427-1430.

Morse AN, Labin LC, Young SB, Aronson MP, Gurwitz JH. Exclusion of elderly women from published randomized trials of stress incontinence surgery. Obstetrics and Gynecol. 2004;104:498-503.

National Bioethics Advisory Commission. Research involving persons with mental disorders that may affect decisionmaking capacity. Volume I (1998). Available at: http://www.george town.edu/research/nrcbl/nbac/capacity/TOC.htm

The Nuremberg Code (1947). Available at: http://ohsr.od.nih. gov/guidelines/nuremberg.html

Office for Human Protections (OHRP). Available at: http:// www.hhs.gov/ohrp/

Olde Rikkert MGM, van den Bercken JHL, ten Have HAMJ, Hoefnagels WHL. Experienced consent in geriatrics research: A new method to optimize the capacity to consent in frail elderly subjects. J Med Ethics. 1997;23:271-276.

Ratzan RM. 'Being old makes you different': The ethics of research with elderly subjects. Hastings Center Report. 1980;10:32-42.

Riecken HW and Ravich R. Informed consent to biomedical research in Veterans Administration hospitals. JAMA. 1982;248:344-348.

Rummans TA, Evans JM, Krahn LE, Fleming KC. Delirium in elderly patients: Evaluation and management. Mayo Clin Proc. 1995;70:989-98.

Sachs GA. Advance consent for dementia research. Alzheimer Disease Associated Disorders. 1994;8(suppl):19-27.

Sachs GA and Cassel CK. Biomedical research involving older human subjects. Law, Medicine and Health Care. 1990;18:234-243.

Sachs GA and Cohen HJ. Ethical challenges to research in geriatric medicine. In Geriatric Medicine: An Evidence-Based Approach, 4th ed. (Springer, 2003).

Sachs GA, Stocking CB, Stern R, Cox DM, Hougham G, Sachs RS. Ethical aspects of dementia research: informed consent and proxy consent. Clin Res. 1994;42:403-412.

Shamoo AE, Khin-Maung-Gyi FA. The use of decisionally impaired people in research. In Ethics of the Use of Human Subjects in Research: A Practical Guide (London: Garland Science, 2002).

Sugarman J, McCrory DC, Hubal RC. Getting meaningful informed consent from older adults: A structured literature review of empirical research. J Am Geriatr Soc. 1998;46: 517-524.

Swift CG. Ethical aspects of clinical research in the elderly. BrJHospMed. 1988;40:370-373.

U.S. Census Bureau. Statistical Abstract of the United States: 2000, 120th ed. (Washington, DC: U.S. Government Printing Office).

Warren JW, Sobal J, Tenney JH, Hoopes JM, Damron D, Levenson S, DeForge BR, Muncie HL. Informed consent by proxy: An issue in research with elderly patients. New Engl J Med. 1986;315:1124-8.

Weyers W. The Abuse of Man: An Illustrated History of Dubious Medical Experimentation (New York: Ardor Scribendi, 2003).

World Medical Association Declaration of Helsinki (1964). Ethical principles for medical research involving human subjects. Available at: http://www.wma.net/e/policy/b3.htm

Zimmer AW, Calkins E, Hadley E, Ostfeld AM, Kaye JM, Kaye D. Conducting clinical research in geriatric populations. Ann Intern Med. 1985;103:276-283.

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